EAN – Research Paper of the Month: April 2026.
Research Paper for April 2026: Efficacy and safety of minocycline in patients with acute ischaemic stroke (EMPHASIS)
Minocycline, a tetracycline antibiotic, has been shown to target post-ischaemic neuroinflammation, potentially improving outcomes after stroke. In this paper, the authors report the results of the EMPHASIS study, a prospective, randomised, double-blind, placebo-controlled trial conducted across 58 neurological centres in China, aimed at evaluating the efficacy and safety of minocycline in addition to routine treatment in patients with acute ischaemic stroke.
