Projects funded by IICN Brain Research funding

The Institute is committed to supporting research projects in neuroscience and seeks to raise funding which may be made available as Grants for such projects.  Grants are usually in the form of one-year Fellowships.

Applications are invited by public advertisements and all applications are rigorously assessed, scored and ranked using an external peer review process. The numbers of projects supported is dependent on the funding available.

Research projects supported by awards between January 2000 and December 2002:
  • Targeted gene deletion in the evaluation of novel therapies for Psychiatric Disease. Principal applicant: Professor JL Waddington
  • Immunopathological studies of the reasons for failure of repair of the blood-brain barrier (BBB) in MS plaques in the brain. Principal applicant: Dr M Mirakhur
  • Genotype-phenotype correlation in “at-risk” Irish family members with Frontotemporal Dementia and Parkinsonism linked to Chromosome 17. Principal applicant: Dr T Lynch
  • Insulin-like growth factor metabolism and neuroendocrine status in Amyotrophic Lateral Sclerosis. Principal applicant: Dr O Hardiman
  • Do patients with non-epileptic seizures (NES) show higher levels of emotional control and alexithymia than patients with epilepsy /match controls? Possible implications for a novel cognitive behaviour therapy model for the treatment of NES. Principal applicant: Dr D McMackin
  • A case-control study of the effects of in utero exposure to anticonvulsant drugs on growth parameters, neurodevelopmentand behaviour. Principal applicant: Dr JI Morrow
  • A study of extracellular fluid (ECF) versus blood serum anti-epileptic drug (AED) levels in medically intractable patients undergoing epilepsy surgery. Principal applicant: Prof Jack Phillips
  • Cathepsin S expression in astrocytomas: its clinical relevance and role in invasion. Principal applicant: Mr Thomas Flannery
  • Molecular and cellular basis of blood-brain barrier Injury in MS: continuing studies. Principal applicant: Dr John Kirk
  • To examine the value of EEG and cerebral blood flow velocity measurements in neonatal encephalopathy in aiding: early identification; timing of brain injury; and more accurate prognostication. Principal applicant: Dr Seán Connolly
  • Magnetic resonance brain imaging-based in vivo measurement of the gyrification index in temporal lobe epilepsy. Principal applicant: Dr Mary Fitzsimons
  • Atherosclerosis, apolipoprotein A and matrix metalloproteinases; a proposal to study their role in the pathogenesis of intracranial aneurysms. Principal applicant: Dr John Caird

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